5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
- Product Name
- 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
- CAS No.
- 124750-53-4
- Chemical Name
- 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
- Synonyms
- TTMB;ENTERPRISESTANDARD;Losartan Impurity 9;Olmesartan TTMB impurity;5-[2-(4-methylphenyl)phenyl]-1-trityltetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;Olmesartan Medoxomil Impurity 24（Losartan Impurity 9）;N-(TRIPHENYLMETHYL)-5-(4'-METHYLBIPHENYL-2-YL)TETRAZOLE;n-(triphenylmethyl)-5-(4'-methylbiphenyl-2-yl-)terazole
- CBNumber
- CB3438158
- Molecular Formula
- C33H26N4
- Formula Weight
- 478.59
- MOL File
- 124750-53-4.mol
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Property
- Melting point:
- 166-169 °C(Solv: ethyl acetate (141-78-6); dichloromethane (75-09-2))
- Boiling point:
- 681.6±65.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly)
- form
- Solid
- pka
- 0.30±0.10(Predicted)
- color
- Off-White
- CAS DataBase Reference
- 124750-53-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
N-Bromosuccinimide Price
- Product number
- T889172
- Product name
- N-Triphenylmethyl-5-[4''-methylbiphenyl-2-yl]tetrazole-d4
- Packaging
- 10mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 093682
- Product name
- 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $341
- Updated
- 2021/12/16
- Product number
- D62492
- Product name
- N-Triphenylmethyl-5-[4??-methylbiphenyl-2-yl]tetrazole-d4
- Packaging
- 10mg
- Price
- $650
- Updated
- 2021/12/16
- Product number
- 093682
- Product name
- 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $756
- Updated
- 2021/12/16
- Product number
- APN0000403
- Product name
- 5-(4'-METHYLBIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $780.15
- Updated
- 2021/12/16
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Chemical Properties,Usage,Production
Chemical Properties
Off-white Solid
Uses
An intermediate in the preparation of labelled Candesartan.
Uses
5-?(4''-?Methyl-?[1,?1''-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole is a reactant in the synthesis of anti-microbial agents.
Synthesis
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole is prepared by the reaction of trityl chloride and 2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl. The specific synthesis steps are as follows:
Dissolve compound 2 (200 g) with stirring at 40°C 700mL of acetone, Aqueous sodium hydroxide solution (40.67 g sodium hydroxide dissolved in 160 mL water) is added, Continue stirring for 1h, A solution of triphenylchloromethane in acetone (270.8 g of triphenylmethyl chloride dissolved in 800 mL of acetone) was initially added dropwise. The solid was added dropwise and gradually evolved into a white turbid liquid. The reaction was monitored by TLC until it was completely filtered off and washed with water to give a solid as intermediate 3. The solid was blow dried at 50°C to give white intermediate 3 (385 g), yield: 95.2%, HPLC: 99.44%.
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Preparation Products And Raw materials
Raw materials
Preparation Products
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Suppliers
View Lastest Price from 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole manufacturers
- Product
- 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-20
- Product
- 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-10
- Product
- 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-09